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HemOnc ingesting combo drugs as individual concepts with xrefs to both components #455

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jsstevenson opened this issue Jan 8, 2025 · 0 comments
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bug Something isn't working priority:high High priority

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@jsstevenson
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jsstevenson commented Jan 8, 2025

Describe the bug

Here's a HemOnc concept for a combo of trimethoprim and sulfamethoxazole:

 {
          "concept_id": "hemonc:517",
          "label": "Trimethoprim-Sulfamethoxazole",
          "aliases": [
            "SMX / TMP",
            "SMZ ( CO )",
            "SMZ-TMP",
            "SMZ-TMP DS",
            "TMP-SMX",
            "TMS",
            "co-trimoxazole",
            "cotrimazole",
            "cotrimoxazole"
          ],
          "trade_names": [],
          "xrefs": [
            "rxcui:10180",
            "rxcui:10829"
          ],
          "associated_with": [],
          "approval_ratings": [
            "hemonc_approved"
          ],
          "approval_year": [
            "1973"
          ],
          "has_indication": []
        }

The problem is that it has xrefs to each individual part, which leads to a combined normalized group. We should take another look at our HemOnc importer.

See dgidb/dgidb-v5#559

Steps to reproduce

n/a

Expected behavior

see above

Current behavior

see above

Acceptance Criteria

  • Fix this specific case
  • Analyze HemOnc for other tells about combo therapies

Possible reason(s)

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Suggested fix

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Branch, commit, and/or version

main

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@jsstevenson jsstevenson added priority:high High priority bug Something isn't working labels Jan 8, 2025
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