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ui.R
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# Fibromine "ui.R" for Shiny Server
# ============================================================================
# Source global objects
# ============================================================================
source("./global.R")
# ============================================================================
# shinyUI()
# ============================================================================
shinyUI(dashboardPage(
dashboardHeader(
title= "Fibromine",
## Logo for the header
tags$li(
imageOutput("logoFibroHead",
inline= TRUE
),
class = "dropdown"
)
),
dashboardSidebar(
introjsUI(), # required for rintrojs to function properly
sidebarMenu(
id = "tabs",
## menuItems
menuItem("Home", tabName= "Home", icon= shiny::icon("home")),
menuItem("Dataset explorer", tabName= "ByDataset", icon= shiny::icon("database"),
menuItem("Transcriptomics datasets", tabName = "ByTransDataset"),
menuItem("Proteomic datasets", tabName = "ByProtDataset")
) %>% add_class("step_1"),
menuItem("Gene explorer", tabName= "ByGene", icon= shiny::icon("dna")) %>% add_class("step_2"),
menuItem("miRNA explorer", tabName= "BymiRNA", icon= shiny::icon("compress-alt")) %>% add_class("step_3"),
menuItem("Protein explorer", tabName= "ByProtein", icon= shiny::icon("arrows-alt")) %>% add_class("step_4"),
menuItem("Gene co-expression", tabName= "GCN", icon= shiny::icon("project-diagram")) %>% add_class("step_5"),
menuItem("Datasets benchmarking", tabName= "Decor", icon= shiny::icon("star"),
menuItem("Benchmarking results", tabName = "BenchRes"),
menuItem("Benchmarking backstage", tabName = "BenchBack")
) %>% add_class("step_6"),
menuItem("Single cell data", tabName= "SingleCell", icon= shiny::icon("braille"),
menuItem("Published studies", tabName = "scStudies"),
menuItem("Search data", tabName = "scData")
) %>% add_class("step_7"),
menuItem("Download data", tabName= "DownData", icon= shiny::icon("download")) %>% add_class("step_8"),
menuItem("FAQ", tabName= "FAQ", icon= shiny::icon("question")) %>% add_class("step_9"),
menuItem("Docs", tabName= "Docs", icon= shiny::icon("book")) %>% add_class("step_10"),
menuItem("About us", icon= shiny::icon("info"),href= "https://www.fleming.gr/research/ibi/researchers/aidinis-lab") %>% add_class("step_11"),
menuItem("Report issues", icon= shiny::icon("github"), href= "https://github.com/dfanidis/Fibromine") %>% add_class("step_12")
)
),
dashboardBody(
tabItems(
# ============================================================================
# Home tab
# ============================================================================
tabItem(tabName= "Home",
wellPanel(
fluidRow(
div(
"Fibromine",
imageOutput("logoFibro",
inline= TRUE
),
style = "font-weight: bold; text-align: center; color: #d42132; font-size: 36px"
)
),
fluidRow(
h3("An interactive multi-omics data mining tool for Idiopathic Pulmonary Fibrosis")
),
fluidRow(
column(
actionButton(
inputId= "introHome",
label= "About the tool",
icon= shiny::icon("info-circle"),
style= "background-color: #008d4c; color: white;
border-color: #008d4c;"
),
bsTooltip(
id= "introHome",
title= "General info about Fibromine",
placement= "bottom"
),
width = 6,
align = "center",
offset = 3
)
),
fluidRow(
column(
includeHTML("./www/aboutIPF.html"),
width= 4
),
column(
includeHTML("./www/aboutFibromine.html"),
tags$script(HTML(
'$(document).keyup(function(event) {
if ($("#geneName").is(":focus") && (event.key == "Enter" && !event.shiftKey)) {
$("#geneNameSearch").click();
}
if ($("#geneNamePPI").is(":focus") && (event.key == "Enter" && !event.shiftKey)) {
$("#geneNameSearchPPI").click();
}
})'
)),
width= 4
),
column(
h2("Useful links"),
tags$hr(),
fluidRow(
column(
tags$a(
imageOutput("gene",
inline= TRUE
),
href= "https://www.ncbi.nlm.nih.gov/gene/",
rel= "noopener noreferrer",
target= "_blank"
),
tags$br(),
tags$a(
imageOutput("ensembl",
inline= TRUE
),
href= "http://www.ensembl.org/index.html",
rel= "noopener noreferrer",
target= "_blank"
),
tags$br(),
tags$a(
imageOutput("uniprot",
inline= TRUE
),
href= "https://www.uniprot.org/",
rel= "noopener noreferrer",
target= "_blank"
),
tags$br(),
width= 6,
# Increase padding to the right to
# avoid colliding of the logo images
# with those in the right column
style= "padding-left:0px;
padding-top:5px;
padding-bottom:5px;
padding-right:2px;"
),
column(
tags$a(
imageOutput("pulmon",
inline= TRUE
),
href= "http://pulmondb.liigh.unam.mx/",
rel= "noopener noreferrer",
target= "_blank"
),
tags$br(),
tags$a(
imageOutput("nupulmon",
inline= TRUE
),
href= "https://www.nupulmonary.org/",
rel= "noopener noreferrer",
target= "_blank"
),
tags$br(),
tags$a(
imageOutput("ipfatlas",
inline= TRUE
),
href= "http://www.ipfcellatlas.com/",
rel= "noopener noreferrer",
target= "_blank"
),
width= 6,
# Increase padding to the left to
# avoid colliding of the logo images
# with those in the left column
style= "padding-left:2px;
padding-top:5px;
padding-bottom:5px;
padding-right:0px;"
),
width= 12
),
fluidRow(
column(
tags$a(
imageOutput("string",
inline= TRUE
),
href= "https://string-db.org/",
rel= "noopener noreferrer",
target= "_blank"
),
tags$br(),
tags$a(
imageOutput("go",
inline= TRUE
),
href= "http://geneontology.org/",
rel= "noopener noreferrer",
target= "_blank"
),
tags$br(),
width= 6
),
column(
tags$a(
imageOutput("lungAgingAtlas",
inline= TRUE
),
href= "http://146.107.176.18:3838/MLAA_backup/",
rel= "noopener noreferrer",
target= "_blank"
),
tags$br(),
tags$a(
imageOutput("emouse",
inline= TRUE
),
href= "http://www.fleming.gr/emouse/",
rel= "noopener noreferrer",
target= "_blank"
),
tags$br(),
width= 6
),
width= 12
),
width= 4
)
)
)
),
# ============================================================================
# Dataset explorer tab
# ============================================================================
# Transcriptomic datasets tabItem
tabItem(tabName= "ByTransDataset",
fluidRow(
includeCSS("./www/styles.css"),
useShinyjs(),
tags$head(includeHTML(("./www/google-analytics.html"))),
fluidRow(
h3("Transcriptomic datasets explorer") %>% add_class("step1_trans"),
),
fluidRow(
column(width=6, align= "center",
actionButton(
inputId= "introTrans",
label= "About",
icon= shiny::icon("info-circle"),
style= "background-color: #008d4c; color: white;
border-color: #008d4c;"
),
bsTooltip(
id= "introTrans",
title= paste0("Info about exploring the transcriptomic datasets"),
placement= "bottom"
),
offset= 3
)
),
shinydashboard::tabBox(
id= "transDatasetsBox",
tabPanel(title= "Datasets",
fluidRow(
tipify(
el= h3("Datasets table",shiny::icon("question-circle")) %>% add_class("step1_trans"),
title= paste0("Click one or multiple rows (they will turn blue) ",
"to choose a dataset(-s) and then press the Search button ",
"to explore. Results are presented at the next 2 tabs of the explorer. ",
"Use the GEO accession, Reference and Platform ",
"column hyperlinks for more information about a dataset."
),
placement= "bottom"
)
),
fluidRow(
column(width= 4,
actionButton(
inputId= "transDtstsSearch",
label= "Search",
icon= shiny::icon("search"),
style="background-color: #d42132; color: white;
border-color: #d42132;"
) %>% add_class("step2_trans"),
bsTooltip(
id= "transDtstsSearch",
title= paste0("Choose one or multiple datasets from ",
"the table below and then press search. ",
"Results are presented at the next 2 tabs of the explorer."
),
placement="bottom"
),
actionButton(
inputId= "clearTransDtstsSearch",
label= "Reset",
icon= shiny::icon("refresh"),
style= " background-color: #008d4c; color: white;
border-color: #008d4c"
) %>% add_class("step3_trans"),
bsTooltip(
id= "clearTransDtstsSearch",
title= "Clear dataset selection.",
placement="bottom"
),
actionButton(
inputId= "selectTransAll",
label= "Select all",
icon= shiny::icon("check"),
style="background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "selectTransAll",
title= paste0("Select all table rows (based on current ",
"used filters). To select specific datasets ",
"click the respective table row."
),
placement= "top"
),
offset= 8
)
),
fluidRow(
column(width= 12,
DT::dataTableOutput("datasetsTable")
)
),
width= 12
), # Close "Datasets" tab
tabPanel(title= "DEA statistics",
fluidRow(
column(width=12,
tipify(
h3("Common DEGs and DEPs",
shiny::icon("question-circle")
),
title= paste0("Common DEGs and respective DEPS across selected ",
"datasets using p-value and FC thresholds ",
"of 0.05 and 1.2 respectively."
)
)
)
),
fluidRow(
column(width=6, align= "center",
actionButton(
inputId= "introTransStats",
label= "About",
icon= shiny::icon("info-circle"),
style= "background-color: #008d4c; color: white;
border-color: #008d4c;"
),
bsTooltip(
id= "introTransStats",
title= paste0("Info about exploration/integration results"),
placement= "bottom"
),
offset= 3
)
),
fluidRow(
column(width=2,
wellPanel(
h5("Change DEA\nthresholds"),
numericInput(
inputId= "pvalCommonIn",
label= "Type a p-value",
value= 0.05,
step= 0.01
),
numericInput(
inputId= "fcCommonIn",
label= "Type a Fold change",
value= 1.2,
step= 0.01
),
actionButton(
inputId= "filterCommon",
label= "Filter",
icon = shiny::icon("filter"),
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "filterCommon",
title= paste0(
"Use the above control panel to change ",
"thresholds and then press this button to ",
"apply changes."
)
)
) %>% add_class("step2_transStats"),
wellPanel(
h5("Pathway\nanalyses"),
helpText("Interrogate one/multiple datasets first."),
radioButtons(
inputId= "paChoice",
label= "Choose a pathway analysis method",
choices= c(
"ORA" = "ora"#,
# "Pre-ranked GSEA" = "preRnk"
)
),
actionButton(
inputId= "paRun",
label="Go",
icon= shiny::icon("cog"),
style="background-color: #d42132; color: white;
border-color: #d42132;"
),
helpText(paste("Note: Filter the 'Database' column of the 'Pathway analysis results'",
"table to interrogate enrichment of terms from different databases",
"including a COVID-19 gene set(!).")
)
) %>% add_class("step3_transStats")
),
column(width=10,
shinydashboard::tabBox(
id= "degStatBox",
tabPanel("Consensus DEGs",
DT::dataTableOutput("degStatsSum",
) %>% withSpinner(color="#008d4c"),
downloadButton(outputId= "degSumAll",
label="Download table .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "degSumAll",
title= "Download the whole table.",
placement= "top"
),
downloadButton(outputId= "degSumFiltered",
label="Download filtered data .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "degSumFiltered",
title= paste0("Filter any column of the table and then press ",
"this button to download the filtered data."),
placement= "top"
)
),
tabPanel("Consensus DEPs coded",
DT::dataTableOutput("depSum",
) %>% withSpinner(color="#008d4c"),
downloadButton(outputId= "depSumDw",
label="Download table .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "depSumDw",
title= "Download the whole table.",
placement= "top"
)
),
tabPanel("Transcriptomics analytically",
uiOutput(outputId= "commonDegsHelp"),
DT::dataTableOutput("degStats",
) %>% withSpinner(color="#008d4c"),
downloadButton(outputId= "degStatAll",
label="Download table .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "degStatAll",
title= "Download the whole table.",
placement= "top"
),
downloadButton(outputId= "degStatFiltered",
label="Download filtered data .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "degStatFiltered",
title= paste0("Filter any column of the table and then press ",
"this button to download the filtered data."),
placement= "top"
),
downloadButton(outputId= "degStatSel",
label="Download selected .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "degStatSel",
title= paste0("Select a number of rows from the above table ",
"and then press this button to download them."),
placement= "top"
)
),
width= 12
) %>% add_class("step1_transStats"), # Close "degStatBox"
shinydashboard::tabBox(
id= "paResBox",
tabPanel("Pathway analysis results",
DT::dataTableOutput("paResTable",
) %>% withSpinner(color="#008d4c"),
downloadButton(outputId= "paResDown",
label="Download results .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "paResDown",
title= "Download the full PA report",
placement= "top"
)
),
width = 12
) # Close "paResBox"
)
),
width= 12
), # Close "DEA statistics" tab
tabPanel(title= "Dataset plots",
fluidRow(
column(width=12,
tipify(
h3("Exploratory plots", shiny::icon("question-circle")) %>% add_class("step1_transConc"),
title= paste0("Choose a dataset from the table below and then press Plot ",
"at the bottom of the respective box to create an exploratory plot."
),
placement= "top"
)
)
),
fluidRow(
column(width=6, align= "center",
actionButton(
inputId= "introTransConc",
label= "About",
icon= shiny::icon("info-circle"),
style= "background-color: #008d4c; color: white;
border-color: #008d4c;"
),
bsTooltip(
id= "introTransConc",
title= paste0("Info about this tab"),
placement= "bottom"
),
offset= 3
)
),
fluidRow(
column(width= 12,
uiOutput(outputId= "datasetsConserningHelp")
)
),
fluidRow(
column(width= 12,
DT::dataTableOutput("datasetsConserning")
)
),
fluidRow(
box(
uiOutput(outputId= "heatmapQCHelp"),
uiOutput(outputId= "heatmapQCstatWarning"),
plotlyOutput(outputId= "heatmapQC",
height= "600px") %>% withSpinner(color="#008d4c"),
actionButton(
inputId= "plotHeatmap",
label= "Plot heatmap",
icon= shiny::icon("paint-brush"),
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
width= 6, title= "Heatmap", status= "primary",
collapsible= TRUE, collapsed= TRUE
),
box(
uiOutput(outputId= "volcanoQCHelp"),
plotlyOutput(outputId= "volcanoQC",
height= "600px") %>% withSpinner(color="#008d4c"),
actionButton(
inputId= "plotVolcano",
label= "Plot volcano",
icon= shiny::icon("paint-brush"),
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
width= 6, title= "Volcano", status= "primary",
collapsible= TRUE, collapsed= TRUE
)
),
width= 12
), # Close "Concerning dataset(-s)" tab
width= 12
), # Close "transDatasetsBox"
width= 12
)
), # Close "ByTransDataset" menu item
# Proteomic datasets tabItem
tabItem(tabName= "ByProtDataset",
fluidRow(
fluidRow(
h3("Proteomics datasets explorer") %>% add_class("step1_protDat"),
),
fluidRow(
column(width=6, align= "center",
actionButton(
inputId= "introProtDat",
label= "About",
icon= shiny::icon("info-circle"),
style= "background-color: #008d4c; color: white;
border-color: #008d4c;"
),
bsTooltip(
id= "introProtDat",
title= paste0("Info about exploring the proteomic datasets"),
placement= "bottom"
),
offset= 3
)
),
shinydashboard::tabBox(
id= "protDatasetsBox",
tabPanel(title= "Datasets",
fluidRow(
tipify(
el= h3("Datasets table",shiny::icon("question-circle")),
title= paste0("Click one or multiple rows (they will turn blue) ",
"to choose a dataset(-s) and then press the Search button ",
"to explore. Results are presented at the next 2 tabs of the explorer. ",
"Use the GEO accession, Reference and Platform ",
"column hyperlinks for more information about a dataset."
),
placement= "bottom"
)
),
fluidRow(
column(width= 3,
actionButton(
inputId= "protDtstsSearch",
label= "Search",
icon= shiny::icon("search"),
style="background-color: #d42132; color: white;
border-color: #d42132;"
) %>% add_class("step2_protDat"),
bsTooltip(
id= "protDtstsSearch",
title= paste0("Choose one or multiple datasets from ",
"the table below and then press search. ",
"Results are presented at the next 2 tabs of the explorer."
),
placement="bottom"
),
actionButton(
inputId= "clearProtDtstsSearch",
label= "Reset",
icon= shiny::icon("refresh"),
style= " background-color: #008d4c; color: white;
border-color: #008d4c"
) %>% add_class("step3_protDat"),
bsTooltip(
id= "clearProtDtstsSearch",
title= "Clear dataset selection.",
placement="bottom"
),
actionButton(
inputId= "selectProtAll",
label= "Select all",
icon= shiny::icon("check"),
style="background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "selectProtAll",
title= paste0("Select all table rows (based on current ",
"used filters). To select specific datasets ",
"click the respective table row."
),
placement= "top"
),
offset= 9
)
),
fluidRow(
column(width= 12,
DT::dataTableOutput("proteomicsTable")
)
),
width= 12
), # Close "Datasets" tab
tabPanel(title= "DEA data",
fluidRow(
column(width=12,
tipify(
h3("Common DEPs",
shiny::icon("question-circle")
),
title= paste0("Common DEPs across selected ",
"datasets."
)
)
)
),
fluidRow(
column(width=6, align= "center",
actionButton(
inputId= "introProtStats",
label= "About",
icon= shiny::icon("info-circle"),
style= "background-color: #008d4c; color: white;
border-color: #008d4c;"
),
bsTooltip(
id= "introProtStats",
title= paste0("Info about exploration/integration results"),
placement= "bottom"
),
offset= 3
)
),
fluidRow(
shinydashboard::tabBox(
id= "depStatBox",
tabPanel("Consensus DEPs",
DT::dataTableOutput("depStatsSum",
) %>% withSpinner(color="#008d4c"),
downloadButton(outputId= "depStatsSumAll",
label="Download table .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "depStatsSumAll",
title= "Download the whole table.",
placement= "top"
),
downloadButton(outputId= "depStatsSumFiltered",
label="Download filtered data .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "depStatsSumFiltered",
title= paste0("Filter any column of the table and then press ",
"this button to download the filtered data."),
placement= "top"
)
),
tabPanel("Proteomics analytically",
DT::dataTableOutput("depStats",
) %>% withSpinner(color="#008d4c"),
downloadButton(outputId= "depStatAll",
label="Download table .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "depStatAll",
title= "Download the whole table.",
placement= "top"
),
downloadButton(outputId= "depStatFiltered",
label="Download filtered data .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "depStatFiltered",
title= paste0("Filter any column of the table and then press ",
"this button to download the filtered data."),
placement= "top"
),
downloadButton(outputId= "depStatSel",
label="Download selected .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "depStatSel",
title= paste0("Select a number of rows from the above table ",
"and then press this button to download them."),
placement= "top"
)
),
width= 12
) %>% add_class("step1_protStats") # Close "depStatBox"
),
width = 12
), # Close "DEA data" tab
width = 12
) # Close "protDatasetsBox"
)
),
# ============================================================================
# Gene explorer tab
# ============================================================================
tabItem(tabName= "ByGene",# class="active",
fluidRow(
column(width=2,
wellPanel(
textAreaInput(
inputId= "geneName",
label= "Type your gene(-s) of interest",
placeholder= "Search by gene name...",
resize= "none"
),
radioButtons(
inputId= "speciesChoice",
label= "Filter by species",
choices= c(
"Both"= "Both",
"Human"= "Human",
"Mouse"= "Mouse"
)
),
actionButton(
inputId= "geneNameSearch",
label="Search",
icon= shiny::icon("search"),
style="background-color: #d42132; color: white;
border-color: #d42132;"
),
bsTooltip(
id= "geneName",
title= paste0("Type one or multiple gene symbols/ ensembl ",
"IDs on the box above. To search for an miRNA, please ",
"provide its name, e.g. hsa-miR-21-5p. ",
"In case of an official HGNC alias given, please choose ",
"the required species below. ",
"Gene search is case in-sensitive and can be filtered using ",
"the radio buttons below. ",
"Non-existent, misspelled names will be auto-removed."),
placement= "bottom"
),
actionButton(
inputId= "geneNameSearchExample",
label="Example",
icon= shiny::icon("play"),
style="background-color: #d42132; color: white;
border-color: #d42132;"
),
actionButton(
inputId= "introGene",
label= "About",
icon= shiny::icon("info-circle"),
style= "background-color: #008d4c; color: white;
border-color: #008d4c;"
),
bsTooltip(
id= "introGene",
title= paste0("Info about the Gene explorer"),
placement= "bottom"
),
helpText("Note: batch search for a great number of genes
can take some time; please, be patient."
)
)
),
column(width=10,
wellPanel(
h3("General information"),
DT::dataTableOutput(outputId= "geneInfo"),
br(),
tipify(
h3("Map to single cell data",
shiny::icon("question-circle")
),
title= paste0("Query for one or multiple protein-coding genes and then ",
"use hyperlinks from the table below to map ",
"the queried genes in same species datasets of NUPulmonary. "
)
),
DT::dataTableOutput(outputId= "geneMapSc")
)
)
),
fluidRow(
shinydashboard::tabBox(
tabPanel(title="Expression data",
fluidRow(
column(width= 12,
tipify(
h3("DEG statistics",
shiny::icon("question-circle")
),
title= paste0("Gene expression statistics ",
"for all datasets where the gene is ",
"detected and/or not filtered out during analysis. ",
"FDR < 0.05 is colored red."
)
),
uiOutput(outputId= "expressionPerGeneHelp")
)
),
fluidRow(
column(width= 12,
DT::dataTableOutput(outputId= "expressionPerGene"),
downloadButton(outputId= "geneStatDown",
label="Download .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
)
)
),
fluidRow(
column(width= 12,
tipify(
h3("DEP data",
shiny::icon("question-circle")
),
title= paste0("DEP data ",
"matching the genes queried."
)
),
uiOutput(outputId= "expressionPerProteinHelp")
)
),
fluidRow(
column(width= 12,
DT::dataTableOutput(outputId= "expressionPerProtein"),
downloadButton(outputId= "prtnStatDown",
label= "Download .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
)
)
)
),
tabPanel(title= "Gene ontology",
fluidRow(
column(width= 12,
tipify(
h3("GO categories", shiny::icon("question-circle")),
title= paste0("GO categories including the ",
"queried genes."
),
placement= "bottom"
),
uiOutput(outputId= "goTableHelp")
)
),
fluidRow(
column(width= 12,
DT::dataTableOutput(outputId= "goTable"),
downloadButton(outputId = "goDown",
label= "Download .xlsx",
style= "background-color: #d42132; color: white;
border-color: #d42132;"
)
)
)
),
tabPanel(title="RefSeq - miRNA",
fluidRow(
column(width= 6,
tipify(
h3("Refseq data", shiny::icon("question-circle")),
title= "Refseq-sourced info for the queried genes.",
placement= "bottom"
),
uiOutput(outputId= "refseqTableHelp")
),
column(width= 6,
tipify(
h3("miRDB data", shiny::icon("question-circle")),
title= "miRDB-sourced info about miRNA-target interactions.",
placement= "bottom"
),
uiOutput(outputId= "miRNAinteractorsTableHelp")
)
),
fluidRow(
column(width=6,